DNA-PKcs participates in the repair of renal tubular epithelial cell injury.
DNA-PKcs 參與腎小管上皮細胞損傷的修復
Ren Fail 2025-07-30
DNA-PKcs 是調控 DNA 修復和細胞週期的重要酵素,在急性腎損傷時會上升,修復後會恢復正常。抑制 DNA-PKcs 會加重粒線體損傷、延長腎損傷和纖維化,還會影響細胞增生。這表示 DNA-PKcs 對腎臟修復很關鍵,有機會成為治療急性腎損傷的新標靶。
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