Lacticaseibacillus paracasei Glu-07: A Promising Probiotic Candidate for the Management of Type 2 Diabetes Mellitus.
Lacticaseibacillus paracasei Glu-07:管理第二型糖尿病的有潛力益生菌候選株
Curr Microbiol 2025-07-22
Early induction of insulin sensitisation treated by tirzepatide: a prospective, single-arm, open-label study in Japanese individuals with obesity and type 2 diabetes.
Tirzepatide 早期誘導胰島素敏感化治療:針對日本肥胖及第二型糖尿病患者的前瞻性、單臂、開放標籤研究
Diabetologia 2025-07-22
Advancing kidney protection in type 1 diabetes: insights from emerging therapies in type 2 diabetes and chronic kidney disease.
在第1型糖尿病中推進腎臟保護:來自第2型糖尿病與慢性腎臟病新興治療的啟示
Expert Rev Clin Immunol 2025-07-22
Is semaglutide cost-effective at closing the gap for Aboriginal and Torres Strait Islander Australians with cardiovascular disease and obesity without type 2 diabetes?
Semaglutide 是否具成本效益於改善患有心血管疾病及肥胖但無第二型糖尿病的澳洲原住民與托雷斯海峽島民的健康差距?
Intern Med J 2025-07-22
Genetic variability in sodium-glucose cotransporter 2 and glucagon-like peptide 1 receptor effect on glycemic and pressure control in type 2 diabetes patients treated with SGLT2 inhibitors and GLP-1RA in the everyday clinical practice.
SGLT2 與 GLP-1 受體基因變異對第二型糖尿病患者使用 SGLT2 抑制劑與 GLP-1RA 日常臨床治療時血糖與血壓控制的影響
Front Endocrinol (Lausanne) 2025-07-22
A decade of progress in type 2 diabetes and cardiovascular disease: advances in SGLT2 inhibitors and GLP-1 receptor agonists - a comprehensive review.
第二型糖尿病與心血管疾病十年進展:SGLT2 抑制劑與 GLP-1 受體促效劑的最新發展—綜合性回顧
Front Endocrinol (Lausanne) 2025-07-22
New Contours, Different Risks: A 9-Year Comparison of Trends and Postoperative Complications in Patients Undergoing Aesthetic Surgery With Prior Bariatric Surgery vs Glucagon-Like Peptide 1 Receptor Agonist Use.
新輪廓,不同風險:接受美學手術患者中,曾有減重手術與使用 Glucagon-Like Peptide 1 Receptor Agonist 之9年趨勢與術後併發症比較
Aesthet Surg J 2025-07-22
Understanding the activation mechanism of GLP-1R/GIPR by dual agonist Tirzepatide via molecular dynamics and protein-peptide binding.
透過分子動力學與蛋白-胜肽結合,解析雙重促效劑 Tirzepatide 活化 GLP-1R/GIPR 的機制
Int J Biol Macromol 2025-07-22
這項研究解析GLP-1R的活化機制,發現其運作方式類似class A GPCRs。研究也說明Tirzepatide能同時結合GLP-1R和GIPR,且關鍵胺基酸對結合很重要。這些成果有助於未來開發更有效的糖尿病和肥胖症藥物。
相關文章PubMedDOI推理
Trajectory of the body weight after drug discontinuation in the treatment of anti-obesity medications.
停用抗肥胖藥物治療後體重變化的軌跡
BMC Med 2025-07-21
Modulation of metabolic, inflammatory and fibrotic pathways by semaglutide in metabolic dysfunction-associated steatohepatitis.
Semaglutide 調節代謝、發炎及纖維化途徑於代謝功能異常相關脂肪性肝炎中的作用
Nat Med 2025-07-21