Exploring the Effects of Effective Parts of Schisandra sphenanthera on the Gut-Brain Axis of Type 2 Diabetes Mellitus Rats Based on Metabolomic and Proteomic Approaches.
基於代謝體學與蛋白質體學方法探討五味子(Schisandra sphenanthera)有效成分對第二型糖尿病大鼠腸-腦軸的影響
Chem Biodivers 2025-06-05
Jiang Tang San Hao Formula exerts its anti-diabetic effect by affecting the gut-microbiota-brain axis.
Jiang Tang San Hao Formula 透過影響腸道-微生物-大腦軸來發揮其抗糖尿病效果。
Phytomedicine 2024-10-10
Hypoglycemic effects of white hyacinth bean polysaccharide on type 2 diabetes mellitus rats involvement with entero-insular axis and GLP-1 via metabolomics study.
白色風信子豆多醣對2型糖尿病大鼠的降血糖效果:透過代謝組學研究探討腸-胰軸及GLP-1的參與。
Int J Biol Macromol 2024-10-11
Bile acids as a key target: traditional Chinese medicine for precision management of insulin resistance in type 2 diabetes mellitus through the gut microbiota-bile acids axis.
膽酸作為關鍵目標:透過腸道微生物-膽酸軸的傳統中醫在2型糖尿病胰島素抗性精準管理中的應用。
Front Endocrinol (Lausanne) 2024-12-25
Ramulus Mori (Sangzhi) alkaloids ameliorate high-fat diet induced obesity in rats by modulating gut microbiota and bile acid metabolism.
Ramulus Mori (Sangzhi) 生物鹼透過調節腸道微生物群和膽汁酸代謝改善高脂飲食誘導的肥胖大鼠。
Front Endocrinol (Lausanne) 2025-01-06
Integrating 16S rDNA and metabolomics to uncover the therapeutic mechanism of electroacupuncture in type 2 diabetic rats.
整合 16S rDNA 和代謝組學以揭示電針療法在 2 型糖尿病大鼠中的治療機制。
Front Microbiol 2025-01-21
Effects of Dioscorea opposita polysaccharides on insulin resistance and gut microbiota in high-fat-diet induced type 2 diabetic rats.
Dioscorea opposita 多醣對高脂飲食誘導的 2 型糖尿病大鼠胰島素抗性和腸道微生物群的影響。
Int J Biol Macromol 2025-02-14
Exploring the Protective Effects of Schisandrin A and Schisandrin B Against Diabetic Cardiomyopathy With a Possible Mechanism Involving Complement Inhibition.
探討 Schisandrin A 和 Schisandrin B 對糖尿病心肌病的保護作用及其可能涉及的補體抑制機制。
Phytother Res 2025-03-09
這項研究探討了五味子果實中的木脂素Schisandrin A (SchA)和Schisandrin B (SchB)對1型糖尿病小鼠心肌病的保護作用。結果顯示,這兩種化合物能顯著降低血糖、改善胰臟功能,並增強心臟功能,減少心室肥大和心肌纖維化。此外,SchA和SchB還展現抗炎和抗氧化特性,可能透過抑制補體反應來保護心臟。這項研究顯示它們在未來治療糖尿病心肌病方面的潛力。
PubMedDOI
Bile-processed Rhizoma Coptidis alleviates type 2 diabetes mellitus through modulating the gut microbiota and short-chain fatty acid metabolism.
經膽汁處理的黃連(Rhizoma Coptidis)透過調節腸道菌群與短鏈脂肪酸代謝,緩解第二型糖尿病(type 2 diabetes mellitus)。
Int Immunopharmacol 2025-04-20
Therapeutic effects of medicinal and food-based traditional herbal couples on type 2 diabetes mellitus based on pharmacodynamics and pharmacokinetics.
基於藥效學與藥物動力學探討藥食同源中藥配伍對第二型糖尿病的治療效果
Front Pharmacol 2025-05-12