Novel insights into the augmented effect of curcumin and liraglutide in ameliorating cisplatin-induced nephrotoxicity in rats: Effects on oxidative stress, inflammation, apoptosis and pyroptosis via GSK-3β.
在改善大鼠順鉑誘導的腎毒性方面，薑黃素和利拉魯肽增效作用的新見解：對氧化壓力、發炎、細胞凋亡和焦亡通過GSK-3β的影響。
Arch Biochem Biophys 2023-12-21
Molecular mechanism of empagliflozin cardioprotection in 5-fluorouracil (5-FU)-induced cardiotoxicity via modulation of SGLT2 and TNFα/TLR/NF-κB signaling pathway in rats.
empagliflozin對5-氟尿嘧啶（5-FU）誘導的心毒性的心臟保護作用的分子機制：透過在大鼠中調節SGLT2和TNFα/TLR/NF-κB信號通路。
Toxicol Res 2024-01-16
Comparative effects of incretin-based therapy on doxorubicin-induced nephrotoxicity in rats: the role of SIRT1/Nrf2/NF-κB/TNF-α signaling pathways.
胰高血糖素類治療對多柔比星誘導的大鼠腎毒性的比較效應：SIRT1/Nrf2/NF-κB/TNF-α 信號途徑的角色。
Front Pharmacol 2024-03-06
Quercetin improves diabetic kidney disease by inhibiting ferroptosis and regulating the Nrf2 in streptozotocin-induced diabetic rats.
槲皮素通過抑制鐵死亡和調節Nrf2改善链脲佐菌素誘導糖尿病大鼠的糖尿病腎病。
Ren Fail 2024-03-14
Cyclosporine-induced kidney damage was halted by sitagliptin and hesperidin via increasing Nrf2 and suppressing TNF-α, NF-κB, and Bax.
西替利普汀和橙皮素通過增加Nrf2並抑制TNF-α、NF-κB和Bax，阻止了細胞色素C誘導的腎損傷。
Sci Rep 2024-04-02
Cyclosporine A (CsA)用於器官移植和自體免疫疾病，但可能傷腎。研究發現橙皮素和席他格列汀對腎有保護作用。大鼠接受席他格列汀或橙皮素治療後，改善腎功能、減少發炎和氧化壓力，保護腎組織。席他格列汀比橙皮素更有效保護腎臟免受CsA損傷。
PubMedDOI
Liraglutide and resveratrol alleviated cyclosporin A induced nephrotoxicity in rats through improving antioxidant status, apoptosis and pro-inflammatory markers.
Liraglutide和白藜蘆醇通過改善抗氧化狀態、減少凋亡和促炎標誌，緩解大鼠細胞色素A誘導的腎毒性。
Biochem Biophys Res Commun 2024-07-10
The Impact of PPAR-γ/Nrf-2/HO-1, NF-κB/IL-6/ Keap-1, and Bcl-2/Caspase-3/ATG-5 Pathways in Mitigation of DOX-Induced Cardiotoxicity in an Animal Model: The Potential Cardioprotective Role of Oxyresveratrol and/or Dapagliflozin.
PPAR-γ/Nrf-2/HO-1、NF-κB/IL-6/Keap-1和Bcl-2/Caspase-3/ATG-5途徑在緩解DOX誘導的心臟毒性中的影響：氧化白藜蘆醇和/或達帕格列酮在動物模型中的潛在心臟保護作用。
Food Chem Toxicol 2024-07-12
Potential roles for eNOS and NrF₂ /HO-1 signaling in the ameliorative effect of lixisenatide on diabetes-induced kidney injury in rats and its amplification by ticagrelor co-administration.
lixisenatide 對糖尿病誘導的腎損傷的改善作用及其與 ticagrelor 共同給藥的增強效應中 eNOS 和 NrF₂ /HO-1 信號通路的潛在角色。
Pharmazie 2024-10-16