Double transgenic neonatal porcine islets as an alternative source for beta cell replacement therapy.
雙重轉基因新生豬胰島作為β細胞替代療法的替代來源。
Proc Natl Acad Sci U S A 2024-11-04
Structural modifications of INGAP-PP present in HTD4010 peptide potentiate its effect on rat islet gene expression and insulin secretion.
INGAP-PP結構修飾在HTD4010肽中的存在,增強其對大鼠胰島基因表現和胰島素分泌的影響。
Peptides 2024-02-14
GLP-1 Analogue-Loaded Glucose-Responsive Nanoparticles as Allies of Stem Cell Therapies for the Treatment of Type I Diabetes.
GLP-1 類似物載荷的葡萄糖反應性納米粒子作為幹細胞治療第一型糖尿病的盟友。
ACS Pharmacol Transl Sci 2024-05-17
Harmine and exendin-4 combination therapy safely expands human β cell mass in vivo in a mouse xenograft system.
Harmine和exendin-4組合療法在小鼠異種移植系統中安全擴大人類β細胞量。
Sci Transl Med 2024-07-10
Two-pronged approach: Therapeutic effect of biological scaffold combined with immune intervention and β-cell replacement on type 1 diabetic mice.
雙重策略:生物支架結合免疫介入與β細胞替代對1型糖尿病小鼠的治療效果。
Diabetes Obes Metab 2025-03-28