Effect of High-Intensity vs Low-Intensity Noninvasive Positive Pressure Ventilation on the Need for Endotracheal Intubation in Patients With an Acute Exacerbation of Chronic Obstructive Pulmonary Disease: The HAPPEN Randomized Clinical Trial.
高強度與低強度非侵入性正壓通氣對急性加重慢性阻塞性肺病患者氣管插管需求的影響:HAPPEN 隨機臨床試驗。
JAMA 2024-09-16
Awake prone positioning for non-intubated patients with COVID-19-related acute hypoxaemic respiratory failure: a systematic review and meta-analysis.
COVID-19相關急性低氧呼吸衰竭非插管患者的清醒俯臥位:系統性回顧與荟萃分析。
Lancet Respir Med 2023-05-22
Impact of Intensity of Continuous Renal Replacement Therapy on Duration of Ventilation in Critically Ill Patients: A Secondary Analysis of the RENAL Trial.
持續性腎臟替代治療強度對危重病患通氣時間的影響:RENAL 試驗的次級分析。
Blood Purif 2023-12-16
Effect of Noninvasive Airway Management of Comatose Patients With Acute Poisoning: A Randomized Clinical Trial.
急性中毒昏迷患者的非侵入性氣道管理對其效果:一項隨機臨床試驗。
JAMA 2023-12-20
The effect of positive pressure ventilation on Acute Kidney Injury in COVID-19 patients with Acute Respiratory Distress Syndrome. An observational study.
COVID-19患者合併急性呼吸窘迫症候群時,正壓通氣對急性腎損傷的影響:一項觀察性研究。
Blood Purif 2024-02-25
Lower vs Higher Oxygenation Target and Days Alive Without Life Support in COVID-19: The HOT-COVID Randomized Clinical Trial.
COVID-19 中低氧與高氧目標對於生存天數無需生命支持的影響:HOT-COVID 隨機臨床試驗。
JAMA 2024-03-22
研究比較COVID-19重症患者,治療目標Pao2達60 mm Hg和90 mm Hg。由於招募緩慢,試驗提前結束。90天內,Pao2達60 mm Hg的患者較不需生命維持支援,死亡率相似。
PubMedDOI
ChatGPT achieves comparable accuracy to specialist physicians in predicting the efficacy of high-flow oxygen therapy.
ChatGPT在預測高流量氧療法療效方面,達到與專科醫師相當的準確性。
Heliyon 2024-06-03
Long-Term Oxygen Therapy for 24 or 15 Hours per Day in Severe Hypoxemia.
重度低氧血症的長期氧氣療法:每日24小時或15小時。
N Engl J Med 2024-09-10
一項多中心隨機對照試驗針對重度低氧血症患者,比較每天24小時與15小時的長期氧氣治療效果。研究招募241名患者,結果顯示兩組在住院或死亡風險上無顯著差異,事件發生率相似(每100人年124.7 vs. 124.5)。危險比為0.99,顯示24小時治療並未提供額外好處。因此,對於重度低氧血症患者,每天24小時的氧氣治療並不比15小時的治療更有效。
PubMedDOI
Frequency of Screening and Spontaneous Breathing Trial Techniques: A Randomized Clinical Trial.
篩檢頻率與自發性呼吸試驗技術:一項隨機臨床試驗。
JAMA 2024-10-09